Disease Protein Prediction with Graph Convolutional Networks
نویسنده
چکیده
Human phenotypes – i.e. our characteristics, conditions and diseases – are not merely a product of our genetic constitution, but rather arise out of an intricate system of interactions between the proteins and other molecules in our cells. 1 This fact has inspired a huge effort to document and understand the network of those protein-protein interactions which we’ll refer to collectively as the protein-protein interaction network or the human interactome. The proteinprotein interaction network can be intuitively represented as an undirected graph: the nodes are proteins and each edge represents a binary physical interaction between proteins.
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